The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes. The goal is to identify noninvasive molecular markers that correlate with oocyte quality and reproductive potential, particularly in women of advanced maternal age.
Women undergoing IVF treatment due to male factor infertility or nonovarian causes.
Age groups: younger women <31 years and older women >38 years.
Regular menstrual cycles.
Willing and able to provide informed consent.
Minors (under 18 years) and women aged 32-37 years
Diagnosis of polycystic ovarian syndrome (PCOS).
History of recurrent pregnancy loss.
Presence of endometriosis.
University of Central Florida
Lead sponsor
The IVF Center at Winter Park
Collaborator