Function Integrity of Neck Anatomy in Thyroid Surgery

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorWuhan University

About this trial

Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy. Although the lobectomy for the unilateral thyroid cancer with contralateral benign nodules is sufficient treatment, some of the patients might suffer from the anxiety of the residual benign thyroid nodule and tend to choose total thyroidectomy, which might be overtreatment.

Thermal ablation has been proven to be effective in achieving nodule shrinkage and being also free from major complications. In our institution, intraoperative RFA was a proposed alternative strategy to treat the contralateral benign nodules after the thyroid lobectomy for the malignant lobe, which was found to have a better quality of life on anxiety, physiological health, social family, psychological and sensory mentions with a considerable complication rate.

Eligibility criteria

Qualifiers

Patients diagnosed with unilateral thyroid carcinoma and contralateral benign nodule confirmed by preoperative ultrasound-guided fine-needle aspiration cytology;

Patients with contralateral nodules ≤ 20mm and located in the thyroid gland;

Patients with clinical node-negative cervical compartment at palpation and neck ultrasound.

Disqualifiers

Previous history of neck surgery

Previous history of neck radiation therapy

Trial design

Treatments tested in this trial

  • Intraoperative thermal ablation

Treatment groups

1,264 Participants
are divided into 2 treatment groups

Sponsors and collaborators