About this trial
This randomized controlled trial will compare the effects of neuroplastic and functional changes of Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) when presented in two periods (2HG; n=24) versus a single period (1HG; n=24) in people with bilateral CP. The 1HG will receive 65 hours of HABIT-ILE over one intervention period; the 2HG will receive 130 hours over two intervention periods, within 6 months apart. Children will be assessed at 6 time points: baseline, three weeks after the start, at 3, 6, 7 and 9 months after the start of the study.
Eligibility criteria
Qualifiers
Children with medical diagnosis of bilateral cerebral palsy
Cognitive capacity and language that allows understanding and following the therapist's instructions.
Manual Ability Classification System (MACS) levels I to III
Bimanual Fine Motor Function (BFMF) levels I to III
Disqualifiers
Severe visual problems
Movement restriction due to orthopedic surgery in less than a year
Treatment with botulinum toxin and/or baclofen pump in the last 6 months
Contraindications to receive transcranial magnetic stimulation (epileptic history, metallic implants, neoplasm, etc.)
Trial design
Treatments tested in this trial
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities
- Hand-Arm Bimanual Intensive Therapy Including Lower Extremities