Fungal Surveillance in Bangladesh

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age0+
SponsorInternational Centre for Diarrhoeal Disease Research, Bangladesh

About this trial

This will be an exploratory descriptive study designed to conduct surveillance for the identification of invasive fungal pathogens among hospitalized patients in Bangladesh at two tertiary care acute-level hospitals. including the Dhaka Medical College Hospital, the Dhaka Hospital of icddr,b, and the National Institute of Cancer Research Hospital (NICRH). Respiratory samples, blood, urine, cerebrospinal fluid, surgical wound infection swabs, and other samples including biopsy tissue specimens will be obtained at intensive care units, general medicine and surgery wards, post-operative care, etc. The collected specimens will be sent to the clinical microbiology laboratories of the surveillance hospitals or to the pathology laboratory (biopsy tissue specimens) to test for Aspergillus, Histoplasms, Candida, Pneumocystis, Cryptococcus, and Mucormycetes. The lab. methods will include microscopy, staining, culture, and biochemical tests mainly and if feasible then some specimens may undergo molecular or immunological methods.

Eligibility criteria

Qualifiers

Admitted/hospitalized patients of any age and gender in tertiary-level acute care hospitals AND

Chronic lung conditions including asthma, COPD

Hemodialysis patients,

diabetes,

Disqualifiers

History of taking antifungal drugs within 2 weeks

Not willing to give consent

Trial design

Treatments tested in this trial

  • Invasive Fungal disease surveillance

Treatment groups

800 Participants
are divided into 2 treatment groups

Sponsors and collaborators

International Centre for Diarrhoeal Disease Research, Bangladesh

Lead sponsor

Centers for Disease Control and Prevention

Collaborator

Institute of Epidemiology, Disease Control and Research

Collaborator