About this trial
This will be an exploratory descriptive study designed to conduct surveillance for the identification of invasive fungal pathogens among hospitalized patients in Bangladesh at two tertiary care acute-level hospitals. including the Dhaka Medical College Hospital, the Dhaka Hospital of icddr,b, and the National Institute of Cancer Research Hospital (NICRH). Respiratory samples, blood, urine, cerebrospinal fluid, surgical wound infection swabs, and other samples including biopsy tissue specimens will be obtained at intensive care units, general medicine and surgery wards, post-operative care, etc. The collected specimens will be sent to the clinical microbiology laboratories of the surveillance hospitals or to the pathology laboratory (biopsy tissue specimens) to test for Aspergillus, Histoplasms, Candida, Pneumocystis, Cryptococcus, and Mucormycetes. The lab. methods will include microscopy, staining, culture, and biochemical tests mainly and if feasible then some specimens may undergo molecular or immunological methods.
Eligibility criteria
Qualifiers
Admitted/hospitalized patients of any age and gender in tertiary-level acute care hospitals AND
Chronic lung conditions including asthma, COPD
Hemodialysis patients,
diabetes,
Disqualifiers
History of taking antifungal drugs within 2 weeks
Not willing to give consent
Trial design
Treatments tested in this trial
- Invasive Fungal disease surveillance
Treatment groups
Sponsors and collaborators
International Centre for Diarrhoeal Disease Research, Bangladesh
Lead sponsor
Centers for Disease Control and Prevention
Collaborator
Institute of Epidemiology, Disease Control and Research
Collaborator