Fusion Imaging in Endovascular Thrombectomy for Acute Ischemic Stroke

ConditionStroke Acute
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRegion Skane

About this trial

Endovascular thrombectomy (EVT) is the standard of care for acute ischemic stroke (AIS) caused by a large vessel occlusion.

Successful recanalization is one of the most important factors for a good patient outcome, especially when obtained within 30 minutes from groin puncture, and the procedural success-rate reaches above 90% at treating centers of excellence. There are however a portion of cases where recanalization is not achieved, which in some cases are attributed to difficult arterial anatomy affecting the ability to catheterize the precerebral target vessel.

In the latest angiography platforms, 3D reconstructions of the aortic, cervical and intracranial arteries from the preprocedural CT angiography can be fused with periprocedural 2D digital subtraction angiography and/or fluoroscopy images, so called 2D/3D Fusion imaging. The preparation steps can be done before patient arrival to the angiography suite and the image fusion can be done in less than a minute during patient preparation. Previous observational studies have shown that the use of fusion imaging during EVT procedures may decrease failed target vessel access and increase procedural success rate and first-pass recanalization rate, without prolonging the procedure.

The purpose of this study is to assess the use of fusion imaging in EVT procedures and its effect on target vessel access, recanalization success-rate and procedure times.

Eligibility criteria

Qualifiers

Age ≥18 years.

Eligible for an EVT procedure

Disqualifiers

Previous inclusion in this study

No access to a preoperative CTA

Trial design

Treatments tested in this trial

  • Standard endovascular thrombectomy with Fusion
  • Standard EVT without Fusion

Treatment groups

300 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Region Skane

Lead sponsor

Örebro Läns Landsting

Collaborator

Helsinki University Central Hospital

Collaborator

University of Turku

Collaborator

Lund University

Collaborator

Insel Gruppe AG, University Hospital Bern

Collaborator