Gastric Feeding Versus Transpyloric Feeding in Infants with Severe Bronchopulmonary Dysplasia, a Crossover Study
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age1-1
SponsorLe Bonheur Children's Hospital
About this trial
Hospitalized infants with severe bronchopulmonary dysplasia (BPD) and feeding intolerance will be randomized to 2 weeks of continuous gastric feeding or continuous transpyoloric feeding. Subjects will crossover after 2 weeks and receive 4 weeks of each feeding mode. Respiratory status will be assessed to determine the optimal feeding mode for each infant.
Eligibility criteria
Qualifiers
Patients born <32 weeks' gestation
Currently admitted to the Le Bonheur NICU
Grad 2 or 3 BPD (positive pressure or intubated at 36 weeks PMA)
Signs of gastroesophageal reflux, chronic aspiration, or other feeding intolerance.
Disqualifiers
Known gastrointestinal anomalies
Unable to tolerate ≥100mL/kg/day enteral feeding
Congenital anomalies likely to alter feeding techniques
Surgical feeding tube in place or expected within the next 8 weeks
Trial design
Treatments tested in this trial
- Gastric feeding
- Transpyloric feeding
Treatment groups
25 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov