Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to map gene(s) involved in pheochromocytoma, and 2) identify genotype-phenotype correlations in patients with pheochromocytoma/paraganglioma of various genetic origins.
diagnosis of pheochromocytoma and or paraganglioma
family member with diagnosis of pheochromocytoma and or paraganglioma
diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
family member with diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
unconfirmed diagnosis of pheochromocytoma and/or paraganglioma or associated condition
The University of Texas Health Science Center at San Antonio
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
Collaborator
The Paradifference Foundation
Collaborator
National Cancer Institute (NCI)
Collaborator