Genetic and Epigenetic Basis of Chronic Wounds
ConditionChronic Wounds
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorUniversity of Pittsburgh
About this trial
This pilot study is designed for chronic wounds that fail to heal in a timely manner carry specific genetic signatures. These genetic signatures will be studied using debrided wound tissue that is removed by the wound care provider as part of standard of care. The reference genomic signature will be evaluated by obtaining blood samples and will be compared with wound debrided tissue genomic signature to understand wound specific genomic changes.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Willing to comply with protocol instructions, including all study visits and study activities.
Chronic wounds (> than four weeks since onset)
Clinically diagnosed diabetic or non-diabetic ulcer.
Disqualifiers
Individuals who are deemed unable to understand the procedures, risks and benefits of the study,(i.e. unable to provide informed consent)
Pregnant females (self-declared) or lactating
Subjects with marked immunodeficiency (HIV/AIDS or immune-suppressive medications)
Prisoners
Trial design
Treatments tested in this trial
- No Interventions
Treatment groups
No treatment groups listed
Sponsors and collaborators
University of Pittsburgh
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator
Source ClinicalTrials.gov