Genetic Investigation of Cancer Predisposition

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorThe University of Texas Health Science Center at San Antonio

About this trial

Clinical information and samples (blood, saliva, and tumor) will be collected from patients with multiple cancers and/or a family history of cancer as well as from affected and unaffected relatives; samples will be systematically sequenced and evaluated for candidate driver mutations.

Eligibility criteria

Qualifiers

Any age

Personal history (with documented diagnosis) of cancer before the age of 50

Personal history of more than one primary cancer

Documented diagnosis of cancer AND family history of that same cancer type or multiple other cancers that do not fit classical criteria of hereditary cancer syndromes

Disqualifiers

Established genetic diagnosis of a known hereditary cancer syndrome that is compatible with the clinical presentation

Incarcerated

Trial design

Treatments tested in this trial

  • DNA or RNA Sequencing

Treatment groups

No treatment groups listed