Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorUniversity Children's Hospital, Zurich
About this trial
Individuals with suspected primary immunodeficiency will be studied and the results compared with healthy controls. Primary immunodeficiency may manifest as recurrent, severe or unusual infections as well as signs and symptoms of immune dysregulation such as autoimmunity or lymphoproliferation.
Eligibility criteria
Qualifiers
Patients: Pediatric patients (in/outpatient or referred) with suspected or confirmed Inborn Errors of Immunity.
Relatives: Healthy or affected biological relatives of enrolled patients.
Controls: Healthy volunteers with no history of chronic immunological, inflammatory, or infectious disease.
Consent: Ability to provide signed informed consent (or guardian consent).
Disqualifiers
None
Trial design
Treatments tested in this trial
- Skin Biopsy
- Mouth Swab or Saliva Collection
- Blood Sampling
Treatment groups
500 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov