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Genicular Nerve Block for Knee Pain in the ED

ConditionKnee Pain
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Pennsylvania

About this trial

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Atraumatic knee pain

>17 years age

X-ray of the knee obtained in the ED

Initial pain score (numeric rating scale) 5-10

Disqualifiers

Fracture or dislocation on x-ray

large knee joint effusion identified on x-ray

allergy or contraindication to local anesthetics

History of local anesthetic systemic toxicity after receiving local anesthetics

Trial design

Design model

Parallel

Treatments tested in this trial

  • Genicular nerve block with bupivacaine and corticosteroids

    Procedure/Surgery

    genicular nerve block with ideal body-weight dosing of bupivacaine 0.5% with 4 mg dexamethasone

  • Standard of Care

    Other intervention

    This involves standard of care pain relief for patients who do not receive the genicular nerve block for knee pain, such as acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids.

Treatment groups

34 Participants
are divided into 2 treatment groups
Group A: Genicular Nerve BlockExperimental treatment 1 intervention
Group B: Standard of CareActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pain level

Measured by numeric rating scale: 0 (minimum value) - 10 (maximum value)

Time frame
1 hour post-enrollment

Secondary outcomes

1

Difference in Duration of Analgesia

Patients will be called back to assess their pain levels

Time frame
24 hours
2

Difference in AP-POQ-RED score

9 question survey study, all questions rated on 0 (minimum) - 10 (maximum) scale. Questions include: pain before and after treatment, pain with activities in and out of bed, emotions (anxiety, fear, helplessness), degree of pain relief in the emergency department, satisfaction.

Time frame
1 hour after enrollment
3

Difference in length of stay in the emergency department

Length of stay in the emergency department is determined from the time the provider first sees the patient to the time the provider discharges the patient.

Time frame
Average 1 hour

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Pennsylvania

Lead sponsor

Source ClinicalTrials.gov
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