Germline Testing for Predisposition to Myeloid Malignancies

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorChristopher Reilly

About this trial

The goal of this research study is to evaluate the feasibility of germline genetic testing using the investigational MyeloGen Gene Panel in adult participants diagnosed with myeloid malignancies.

Eligibility criteria

Qualifiers

Age of 18 years or older

Participants must have histologically confirmed myeloid malignancy OR bone marrow failure within the last 6 months prior to screening.

Ability to understand and provide a signed and completed consent document in English.

Disqualifiers

Participants who cannot safely undergo clinically indicated skin biopsy as adjudicated by the study team.

Participants who have previously undergone germline genetic testing for predisposition to myeloid malignancies

Trial design

Treatments tested in this trial

  • MyeloGen Gene Panel

Treatment groups

200 Participants
are divided into 1 treatment group

Sponsors and collaborators

Christopher Reilly

Lead sponsor

Dana-Farber Cancer Institute

Sponsor institution

Broad Institute of MIT and Harvard

Collaborator