Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age55-80
SponsorThe Hong Kong Polytechnic University
About this trial
Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.
Eligibility criteria
Qualifiers
Presence of moderate to severe bilateral glaucomatous optic neuropathy (GON) from primary open-angle (including normal tension) or angle-closure glaucoma, as determined by an ophthalmologist, with abnormal Glaucoma Hemifield Test on standard Humphrey Field Analyzer 24-2 testing and matching nerve-fiber layer thinning on optical coherence tomography;
Stable vision and visual field loss for at least 3 months;
With a best-corrected distance acuity of 6/12 or better (equivalent to 0.3 logMAR acuity or better to confirm that participant's central vision is preserved);
With a cognitive functional score of 22 or above in the Montreal Cognitive Assessment - Hong Kong version (to confirm participants' intact cognitive function).
Disqualifiers
Advanced glaucoma with GON of median deviation worse than -25 decibel;
Ocular diseases other than glaucoma (e.g., age-related macular degeneration, diabetic retinopathy, and moderate to severe cataract);
Severe medical problems (e.g., stroke, Parkinson's disease) or self-reported neurological (e.g. brain surgery, brain tumor and peripheral neuropathy), or cognitive disorders (e.g., diagnosed dementia or cognitive impairment);
Physical impairments (e.g. need the use of orthopedic and mobility aids) or physical limitations restricting them from independent walking;
Trial design
Treatments tested in this trial
- Action video game training
- Conventional physical training
Treatment groups
56 Participants
are divided into 2 treatment groupsSponsors and collaborators
The Hong Kong Polytechnic University
Lead sponsor
University of Waterloo
Collaborator
The University of Hong Kong
Collaborator
University of Leicester
Collaborator
Source ClinicalTrials.gov