About this trial
This prospective observational study will evaluate the association between the time interval since the last dose of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and residual gastric contents before elective surgery. Adult patients receiving GLP-1 RAs and scheduled for elective non-cardiac surgery under general anesthesia will undergo preoperative point-of-care gastric ultrasound. The study will assess whether longer GLP-1 RA cessation intervals are associated with lower ultrasound-estimated gastric volume and a lower frequency of high-risk gastric contents. Body mass index will also be evaluated as a potential modifier of this association.
Eligibility criteria
Qualifiers
Adults aged 18 years or older.
Patients receiving a glucagon-like peptide-1 receptor agonist.
Patients scheduled for elective non-cardiac surgery requiring general anesthesia.
Patients able to provide written informed consent.
Disqualifiers
Emergency surgery.
History of prior gastric surgery.
Known gastroparesis or severe gastroesophageal reflux disease.
Declined or unable to provide written informed consent.
Trial design
Treatments tested in this trial
- GLP-1 RA Cessation Interval