Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorTanta University
About this trial
This study aims to compare the efficacy and outcomes of perineural injection with 5% dextrose, local ozone and glucocorticoid injection in the management of carpal tunnel syndrome.
Eligibility criteria
Qualifiers
Adults aged 18-65 years with a clinical diagnosis of mild to moderate Carpal Tunnel Syndrome .
Clinical diagnosis of mild to moderate Carpal Tunnel Syndrome , as classified by Bland neurophysiological classification scale: Mild Carpal Tunnel Syndrome : Slow Distal Sensory Latency(≥3.6 ms), Normal Distal Motor Latency(< 4.5 ms)
Moderate Carpal Tunnel Syndrome : Slow Distal Sensory Latency (≥ 3.6 ms), Slow Distal Motor Latency (4.5 - 6.4 ms)
Failure to respond to conservative treatments (e.g., splinting, activity modification, or oral medications) for at least 6 weeks.
Disqualifiers
Patient refusal.
Severe Carpal Tunnel Syndrome requiring surgical intervention, as defined by the Bland neurophysiological classification scale: Severe Carpal Tunnel Syndrome: Absent Distal Sensory Latency and Slow Distal Motor Latency (4.5 - 6.4 ms)
Previous corticosteroid injection for Carpal Tunnel Syndrome within the last 6 months.
History of wrist trauma, surgery or anatomical abnormalities.
Trial design
Treatments tested in this trial
- Perineural injection with 5% dextrose (D5W).
- Local ozone injection
- Local glucocorticoid injection (dexamethasone).
Treatment groups
105 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov