Glycaemic Response of Arabic Bread

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Nottingham

About this trial

Bread remains one of the most widely consumed staple foods worldwide, with wheat flour serving as its traditional foundation. However, the widespread dependence on refined wheat-based bread has paralleled the rising prevalence of type 2 diabetes (T2D), partly owing to its high glycaemic index (GI), which results in rapid increases in blood glucose levels. Enhancing the nutritional quality of bread, therefore, represents an important target for dietary intervention.

Developing alternative flour blends for bread production presents a potential strategy for improving glycaemic control and supporting glucose homeostasis. Accordingly, this clinical trial aims to determine whether the partial replacement of wheat flour with legume flours, including chickpea, pea, and lentil, in Arabic bread formulations can lower glycaemic responses compared with traditional Arabic wheat bread.

Eligibility criteria

Qualifiers

Participants will be adults living with overweight or obesity (Body Mass Index [BMI] > 25 kg/m²).

Participants will be of any gender.

Participants will be aged 18 to 65.

Participants will be from any sociodemographic background.

Disqualifiers

Those with food allergies or intolerances to any of the study ingredients, including wheat, chickpeas, lentils, or peas, will not be eligible.

Individuals with a known diagnosis of metabolic or chronic health conditions, such as diabetes, insulin resistance, hypertension, or phenylketonuria, will be excluded due to the potential impact on glycaemic control and study outcomes.

Participants with a fasting blood glucose level of above 7.0 mmol/L.

Use of medications that influence blood glucose levels (e.g., corticosteroids, antipsychotics, antiviral protease inhibitors) or substances that interfere with digestion and absorption (such as laxatives or fibre supplements) will result in exclusion.

Trial design

Treatments tested in this trial

  • Control Bread
  • Chickpea-Enriched Arabic Bread
  • Pea-Enriched Arabic Bread
  • Lentil-Enriched Arabic Bread

Treatment groups

14 Participants
are divided into 2 treatment groups

Sponsors and collaborators