Growth and Feeding Tolerance in Premature Infants
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age28-31
SponsorChildren's Hospital and Institute of Child Health, Multan
About this trial
The main purpose of the study is to evaluate the effect of early human milk fortification versus delayed fortification on growth and feeding tolerance in premature infants.
Eligibility criteria
Qualifiers
Preterm infants born at 28-31+6 weeks' gestation and/or birth weight1000-1500g.
Exclusively receiving mother's own milk or donor human milk.
No major congenital anomalies, severe sepsis, or NEC at enrollment.
Parental/guardian consent
Disqualifiers
Extremely pre-term infants
Infants with congenital gastrointestinal malformations or metabolic disorders.
Infants with confirmed necrotizing enterocolitis(NEC)Stage II/III or intestinal perforation before enrollment (as these cases indicate significant gastrointestinal morbidity that may interfere with feeding tolerance and growth assessment).
Infants whose parents decline participation.
Trial design
Treatments tested in this trial
- early initiation of human milk fortification on feeding tolerance
Treatment groups
96 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov