About this trial
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a personal history of gestational diabetes (high blood sugar in pregnancy) at the University of Missouri. The aim of the study is to advance understanding of how growth hormone affects beta-cells and risk factors for developing gestational diabetes.
Eligibility criteria
Qualifiers
Singleton, full term pregnancy within the past 5 years
Body mass index ≥18.5 kg/m2 and <45.0 kg/m2
Gestational Diabetes Group: History of gestational diabetes in the most recent pregnancy
Control Group: no history of gestational diabetes
Disqualifiers
Pregnant, planning to become pregnant during the study, or breastfeeding
Current diagnosis or history of type 1 or type 2 diabetes
Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)
History of bariatric surgery
Trial design
Treatments tested in this trial
- Not listed