About this trial
The purpose of the research study is to better understand how beta-cells (cells in the pancreas that make insulin and help regulate blood sugar) respond to growth hormone in people with a family history of type 2 diabetes at the University of Missouri. Our aim is to advance understanding of how growth hormone affects beta-cells and risk factors for developing type 2 diabetes.
Eligibility criteria
Qualifiers
18 to 59 years old
body mass index ≥30.0 kg/m2 and <45.0 kg/m2
Family history of type 2 diabetes: first degree relative with type 2 diabetes
Control group: no family history of type 2 diabetes
Disqualifiers
Pregnant, planning to become pregnant during the study, or breastfeeding
Current diagnosis or history of type 1 or type 2 diabetes
Use of medications that can impact the study outcomes (e.g., GLP-1 receptor agonists)
History of bariatric surgery
Trial design
Treatments tested in this trial
- Not listed