Gut Microbiota of Preterm Infants and Full-term Infants at Early Life
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-4
SponsorXinhua Hospital, Shanghai Jiao Tong University School of Medicine
About this trial
The aim of this study is to obtain a longitudinal view of the gut microbial establishment of a cohort of 51 preterm (PT) infants compared to 50 full-term (FT) infants from birth to 90 days of age, and to identify key clinical factors that affect the establishment of neonatal microbiome.
The hypothesis of the investigators is that the gut microbiota progression of PT group and FT group is different in diversity and composition. Antibiotics and its usage duration is likely the main factor disturbing the colonization and development of the gut microbiome of PT infants.
Eligibility criteria
Qualifiers
gestational age <37 weeks;
no gastrointestinal tract disorders, metabolic diseases, or viral hepatitis;
hospital stay > 7 days;
Disqualifiers
NICU stay less than 7 days
Necrotizing enterocolitis infant
Full-term healthy infants;
gestational age >37 weeks;
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Source ClinicalTrials.gov