ConditionHeart Transplantation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University of Vienna
About this trial
To investigate whether the use of haemoadsorption (HA) on cardiopulmonary bypass during heart transplantation (HTX) has an effect on circulating cytokine levels for the first 120 hours after HTX and induces a decreased inflammatory response, increased anti-inflammatory response or immunosuppressive response. Additionally, the influence of HA on primary graft dysfunction, postoperative cerebral dysfunction, postoperative fluid accumulation, renal dysfunction, duration of mechanical ventilation, length of ICU-stay and 30-day mortality should be investigated
Eligibility criteria
Qualifiers
Adult patients undergoing heart transplantation
Disqualifiers
Declined informed consent
Age < 18 years#
Receiving antileukocyte drugs
Receiving TNF-α Blockers, immunosuppressive drugs (e.g. tocilizumab)
Trial design
Treatments tested in this trial
- CytoSorb Adsorber
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov