Haemoadsorption During Heart Transplantation

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMedical University of Vienna

About this trial

To investigate whether the use of haemoadsorption (HA) on cardiopulmonary bypass during heart transplantation (HTX) has an effect on circulating cytokine levels for the first 120 hours after HTX and induces a decreased inflammatory response, increased anti-inflammatory response or immunosuppressive response. Additionally, the influence of HA on primary graft dysfunction, postoperative cerebral dysfunction, postoperative fluid accumulation, renal dysfunction, duration of mechanical ventilation, length of ICU-stay and 30-day mortality should be investigated

Eligibility criteria

Qualifiers

Adult patients undergoing heart transplantation

Disqualifiers

Declined informed consent

Age < 18 years#

Receiving antileukocyte drugs

Receiving TNF-α Blockers, immunosuppressive drugs (e.g. tocilizumab)

Trial design

Treatments tested in this trial

  • CytoSorb Adsorber

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators