About this trial
The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS). The main questions it aims to answer are:
* Does hamstring strengthening reduce the looseness of the knee joint in HSD/hEDS? * Does hamstring strengthening improve clinical outcomes like pain in people living with HSD/hEDS?
Participants will:
* Attend two exercise classes per week for 12 weeks. * Visit the laboratory every 4-6 weeks for testing.
Eligibility criteria
Qualifiers
Reported diagnosis of HSD or hEDS by a physician
Meet the 2017 International Diagnostic Criteria for HSD and hEDS
Clearance to participant in exercise participation, determined using the Get Active Questionnaire
Disqualifiers
Other acquired or hereditary connective tissue disorder (i.e., rheumatoid arthritis, Marfan syndrome, etc.)
Currently experiencing daily knee pain
Prior knee injury or surgery
Intra-articular knee injection in the last 12 months
Trial design
Treatments tested in this trial
- Progressive resistance exercise with an emphasis on eccentric hamstring loading.