Health Effects of Grain Foods in Adults

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-60
SponsorPurdue University

About this trial

This study will assess the effects of eating whole grain foods versus refined grain foods with different amounts of added sugar. It is hypothesized that a diet including grain products will have beneficial effects on taste hedonics, appetite, food/energy intake, body weight, blood pressure, acute and chronic glycemia and acute and chronic lipemia compared to customary diets controlling for added sugars, saturated fats and sodium.

Eligibility criteria

Qualifiers

male and female; 21 to 60 years old; Hemoglobin A1c concentration between 5.7 and 6.4%

Prefer no use of medications, but if on medication, must have been on a stable dose for 3 months and plan to remain at the same dose for the duration of the trial.

low customary intake of whole grain foods (less than 2 servings per day) and high energy from added sugar (greater than 10% energy).

Disqualifiers

Grain or dairy sensitivities or allergies or celiac disease; sensitivity or allergy to other foods that would result in refusal to eat a class of foods.

smoker

intended weight loss or gain during the study period; intended change of activity level during the study period

use of blood thinners

Trial design

Treatments tested in this trial

  • High Whole Grain, Low Sugar
  • Low Whole Grain, Low Sugar
  • High Whole Grain, High Sugar
  • Low Whole Grain, High Sugar

Treatment groups

120 Participants
are divided into 4 treatment groups

Sponsors and collaborators

Purdue University

Lead sponsor

Grain Foods Foundation

Collaborator