Health Effects of Ultra-processed Food Intake
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-60
SponsorGöteborg University
About this trial
Ultra-processed food (UPF) intake has been related to negative health effects and incresed energy intake in previous intervention studies. Thus, previous studies have seen weight gain from higher UPF intake which obscures the potentital to see effects on cardiometabolic biomarkers, independent of weight changes. The overall aim of this project is to study the causal effects of a high UPF diet, compared to a nutrient-matched low UPF diet, on appetite and cardiometabolic health in a weight-stable context.
Eligibility criteria
Qualifiers
Age 20-60 years
Weight stable (less than 5% weight change in the past 3 months)
No plans to change weight
Willing to eat the study diet and a mixed diet
Disqualifiers
Allergy or intolerance to foods included in the study. Participants with lactose intolerance treated with lactase may participate if they take enzymes.
BMI <18.5 or >35 kg/m²
Use of medications known to significantly affect appetite (e.g., oral corticosteroids, antipsychotic medications, or GLP-1 receptor agonists)
Use of lipid-lowering medications (e.g., statins or PCSK9 inhibitors)
Trial design
Treatments tested in this trial
- Diet high in UPF
- Diet low in UPF
Treatment groups
40 Participants
are divided into 2 treatment groupsSponsors and collaborators
Göteborg University
Lead sponsor
Chalmers University of Technology
Collaborator
Karolinska Institutet
Collaborator
Source ClinicalTrials.gov