About this trial
Accumulating evidence demonstrates that breathing air pollutants leads to devastating increases in sickness and death worldwide over time. However, there is little data comparing the effects of different types of air pollution on health. In Canada, traffic-related air pollution and wood smoke (wildfires and wood burning for heating) are very common air pollutants. This study aims to safely complete a controlled human exposure study to test how these air pollution types acutely affect health.
Eligibility criteria
Qualifiers
Age 19-40
Healthy, with no history of respiratory disease
Lifetime non-smoker and non-vaper.
Disqualifiers
Pregnant, planning to become pregnant, or breastfeeding during the study period (confirmed through pregnancy tests at each visit if applicable)
Frequent WS or DE exposures (e.g. home fireplace used for heating/cooking, or employment in transportation, mining, or as a firefighter).
Trial design
Treatments tested in this trial
- Filtered Air (FA)
- Wood Smoke (WS)
- Diesel Exhaust (DE)
- Diesel Exhaust and Wood Smoke (DEWS)