Hearing and Brain Development Cohort in Children and Adolescents

ConditionHearing Loss

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

AgeUp to 18

SponsorShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

About this trial

This bidirectional observational cohort study aims to establish a Hearing and Brain Development (HBD) cohort in children and adolescents with hearing loss across different hearing management pathways, including hearing aid fitting, cochlear implantation, auditory brainstem implantation, gene therapy, and follow-up without intervention, as well as in a normal-hearing control group. Participants will undergo longitudinal assessments of hearing, speech, language, neurodevelopment, and multimodal brain function.

Eligibility criteria

Qualifiers

Age no more than 18 years.

For the HA/CI/ABI/GT/FU groups: behavioral or pure-tone hearing threshold >=20 dB HL, or air-conduction ABR >=35 dB nHL; For the normal-hearing control group: participants diagnosed as normal hearing by experienced physicians.

Disqualifiers

Inability to cooperate with study testing procedures.

Trial design

Treatments tested in this trial

Not listed

Trial groups

5,000 Participants

are grouped into 6 trial groups

Trial groups

See each trial group below.

Sponsors and collaborators

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Lead sponsor

Source ClinicalTrials.gov