HELIOS Advanced: Human Oocyte Illumination to Enhance Development

ConditionIVF Outcomes
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-48
SponsorColumbia University

About this trial

Oocytes need a lot of energy to complete meiosis and fertilize successfully. As women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for eggs and embryos to develop normally. One possible way to help is with a gentle light treatment called photobiomodulation (PBM). This uses a special type of red light that boosts energy production in cells and helps them stay healthy. This study will test whether adding this light treatment during in vitro fertilization (IVF) can improve embryo growth and pregnancy outcomes.

Eligibility criteria

Qualifiers

Female age between 18-48 years at the time of the IVF/ICSI cycle

Undergoing blastocyst culture

Using own oocytes

Has at least two oocytes available for randomization

Disqualifiers

Use of donor oocytes or gestational carrier

Concurrent experimental laboratory inventions outside of protocol

Refusal of randomization or request for non-standard handling

Trial design

Treatments tested in this trial

  • Photobiomodulation

Treatment groups

270 Participants
are divided into 2 treatment groups

Sponsors and collaborators