Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity Hospital, Limoges
About this trial
Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the normalization of macro-hemodynamic parameters. This interventional study evaluates the impact of measuring microcirculation parameters by nurses on patient prognosis through early initiation of vascular filling.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Admitted to the Emergency Department for suspected Sepsis for less than 6 hours according to international Sepsis-3 definitions (high probability of infection defined by a fever greater than or equal tol to 38.3°C with a suspected infectious source + Score NEWS 2 greater than or equal to 2)
Affiliated to a social security system
Having agreed to participate in this study
Disqualifiers
Patient with arterial hypotension (SBP ≤ 100 mmHg) on admission
Patient having already received a 500mL filling test over 30 minutes
Patients moribund according to the investigator
Pregnancy or breastfeeding
Trial design
Treatments tested in this trial
- measurement of the peripheral perfusion index and marbling assessment
Treatment groups
556 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov