Hemodynamic Monitoring and Fluid Responsiveness in Venovenous Extracorporeal Membrane Oxygenation (VV ECMO) - "HemodynamECMOnitoring-VV Study"

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorMedical University of Vienna

About this trial

In extracorporeal membrane oxygenation (ECMO), blood is drawn out of the body via tubes, oxygenated in an artificial lung; and then pumped back into the blood vessels. This allows the supply of oxygen-rich blood to the organs (brain, heart, lungs, kidneys, liver, intestines, etc.) to be maintained.

Continuous monitoring of cardiac function and circulatory status (blood pressure, blood flow to organs) is very important in intensive care medicine in order to control the administration of circulation-supporting medication and infusions. Various devices are routinely used for this task. However, in the specific situation of ECMO treatment, the measurements of these devices could be affected due to the artificial circulation; outside the body.

The purpose of this study is therefore to test the accuracy of different methods of circulation monitoring during ECMO treatment.

Eligibility criteria

Qualifiers

Patient receiving VV-ECMO support

Age 18 - 75 years

Disqualifiers

Pregnancy

Conditions not allowing for passive leg raising maneuvers, e.g. "open abdomen", known or suspected elevation of intracranial pressure, recent leg or spinal trauma or orthopedic conditions not permitting leg raising

Known ischemic or hemorrhagic stroke within 3 months prior to study enrollment.

Trial design

Treatments tested in this trial

  • Transthoracic Echocardiography
  • Uncalibrated Pulse Contour Analysis
  • Transpulmonary Thermodilution/Calibrated Pulse Contour Analysis
  • Esophageal Doppler
  • Bioreactance
  • Passive Leg Raising
  • Vena Cava Ultrasound
  • End-expiratory /-inspiratory occlusion test
  • Fluid bolus

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators