Hemoperfusion in Critical Patients With Septic Multiorgan Dysfunction Syndrome.
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorHospital Clinic of Barcelona
About this trial
Low-level interventional clinical trial to evaluate the effectiveness and safety of extracorporeal support with hemoperfusion in critical patients with septic multiorgan dysfunction syndrome.
Eligibility criteria
Qualifiers
Sepsis of abdominal origin with controlled infectious focus.
Noradrenaline dose> 0.5 µg / kg / min to maintain adequate organ perfusion after optimization of fluid therapy.
Dysfunction of two or more organs with SOFA ≥ 9 (5).
Blood lactate ≥ 2 mmol / L.
Disqualifiers
Age under 18 years or over 80 years.
Pregnancy or breastfeeding.
Terminally ill patients or with a life expectancy of less than 48 hours.
Thrombocytopenia <60,000 / mm3.
Trial design
Treatments tested in this trial
- Extracorporeal support with haemoperfusion
- Conventional treatment
Treatment groups
48 Participants
are divided into 2 treatment groupsSponsors and collaborators
Hospital Clinic of Barcelona
Lead sponsor
Hospital General Universitario de Castellón
Collaborator
Hospital Universitario La Paz
Collaborator
Hospital de Granollers
Collaborator
Hospital General Universitario Santa Lucía
Collaborator
Source ClinicalTrials.gov