Heparin Alone vs. Heparin-Aspirin Combo in Free Flap Survival
ConditionComplication,Postoperative
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorAga Khan University
About this trial
This randomized clinical trial aims to compare the effectiveness of heparin alone versus combination therapy of Heparin- Aspirin in improving free flap survival in patients undergoing reconstructive surgery. Participants will be randomly assigned to receive either heparin or a combination therapy, and the primary outcome measure will be the survival rate of the free flap at various time points post-surgery
Eligibility criteria
Qualifiers
Patients undergoing free flap surgery
Age between 18 and 70 years
Disqualifiers
Known hypersensitivity to heparin or aspirin
History of bleeding disorders
Concurrent use of other anticoagulant or antiplatelet medications
Severe renal or hepatic impairment
Trial design
Treatments tested in this trial
- LMW Heparin 5000 U/ML-Aspirin 75 MG
- LMW Heparin 5000 U/ML
Treatment groups
126 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov