Hepatic Lipid Metabolism-Alcohol Use Disorder

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-100
SponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

About this trial

Patients with hepatic steatosis due to alcohol will be offered liver biopsies when they enter a detoxification program. The first biopsy will occur in the first week of admission and the second in the fourth week when the steatosis has resolved. The hepatic transcriptome will be compared,

Eligibility criteria

Qualifiers

Any individual >=18 years of age who is enrolled in 14-AA-0181 and is seeking inpatient treatment.

Vibration Controlled Elastography parameters with initial CAP of >295dB/m.

Disqualifiers

Pregnancy

Existing diagnosis of hyperlipidemia or essential hypertension

Hemoglobin A1c >= 6.5%

Waist to hip ratio: >=0.90 in males, >=0.85 in females

Trial design

Treatments tested in this trial

  • Liver biopsy

Treatment groups

25 Participants
are divided into 1 treatment group