The goal of this project is to characterise the heterogeneity of all cell populations (tumour cells, stromal and immune microenvironment) present in the tumor and their normal (and leucoplasic) counterparts by scRNAseq in OSCC patients.
I1. Male or female at least 18 years old.
I2. Patient with OSCC and undergoing surgery at the Centre Léon Bérard.
I3. Patient who has agreed to participate in this research and sign consent.
I4. Patient affiliated to a medical insurance.
NI1. Pregnant or nursing woman.
NI2. Contraindication to general anesthesia.
NI3. Suspicion of rare tumor of particular histology other than squamous cell carcinoma (Sarcoma...).
NI4. Patient under curatorial or guardianship or placed under the protection of justice.