Hetrombopag in Promoting Platelet Engraftment After Auto-HSCT in Children With Neuroblastoma

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeUp to 18
SponsorBeijing Children's Hospital

About this trial

The goal of this clinical trial is to learn if hetrombopag promotes platelet engraftment in neuroblastoma children undergoing autologous hematopoietic stem cell transplantation. The main question it aims to answer is:

· Does drug hetrombopag promote platelet engraftment? Participants will take hetrombopag every day for 6 weeks or until platelet \> 100\*10\^9/L.

Eligibility criteria

Qualifiers

Age<18 years old;

Diagnosed as neuroblastoma;

ECOG ≤ 2;

First time receiving autologous hematopoietic stem cell transplantation;

Disqualifiers

ALT/AST > 3 ULN, or TBIL > 1.5 ULN;

Have experienced congestive heart failure, arrhythmia, peripheral arteriovenous thrombosis requiring medication treatment within one year prior to enrollment, or have experienced myocardial infarction or cerebral infarction within three months prior to enrollment;

Suffering from thromboembolic diseases;

Other situations that are not suitable for inclusion in the study determined by researchers.

Trial design

Treatments tested in this trial

  • Hetrombopag

Treatment groups

30 Participants
are divided into 1 treatment group

Sponsors and collaborators