Hexadecanal as an Addon to Cognitive Processing Therapy for PTSD

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorTel Aviv University

About this trial

This RCT investigates whether Cognitive Processing Therapy, a first line treatment for PTSD, can be enhanced by the use of the odor molecule Hexadecenal (HEX). HEX is secreted from body odor and has been shown to promotes psychological well-being and positive social interaction. For the active group Hex will be diffused in the treatment room during all treatment sessions. For the control group a vehicle placebo molecule will be diffused. Both therapists and patients will be blind to study condition.

Eligibility criteria

Qualifiers

Diagnosis of PTSD according to DSM-5

Age 18 years and over

Eligible for CPT treatment at the National Center for Traumatic Stress and Resilience

Disqualifiers

Bipolar disorder, psychosis, neurological disorders

Drug Addiction

Parallel psychotherapy

Congenital or acquired anosmia.

Trial design

Treatments tested in this trial

  • Cognitive Processing Therapy + Hexadecanal
  • Hexadecanal - Molecule Distribution in the Therapy room

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Tel Aviv University

Lead sponsor

Weizmann Institute of Science

Collaborator