HFNC Compared With Facial Mask in Patients With Chest Trauma Patients
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20-99
SponsorNational Taiwan University Hospital
About this trial
Guidelines for noninvasive ventilation (NIV) recommend continuous positive airway pressure in patients with thoracic trauma who remain hypoxic . However, no any suggestion was applied for high flow nasal cannula (HFNC). Therefore, Our aim was to determine whether HFNC reduces intubation in severe trauma-related hypoxemia.
Eligibility criteria
Qualifiers
severe hypoxemic respiratory failure [Arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen fraction(FiO2) <300 mmHg]
with a respiratory rate >25 breaths/minute and difficulty breathing, or respiratory distress
PaCO2 of 45 mmHg or higher (if the patient requires emergency surgery with endotracheal intubation and mechanical ventilation, the time of inclusion will be the start of the post-extubation period. (Note: For patients who receive emergency trauma surgery with endotracheal intubation and mechanical ventilation, the time of inclusion assessment will be 72 hours after extubation.)
Disqualifiers
Patients with a Glasgow Coma Scale less than 8 or severe brain injury.
Patients with any contraindications to non-invasive ventilation, including acute gastrointestinal bleeding, upper airway obstruction, or hemodynamic instability.
Facial trauma involving skull base fractures, facial bone fractures, or orbital floor fractures.
Severe injuries involving the nasal sinuses.
Trial design
Treatments tested in this trial
- high flow nasal cannula
- Oxygen mask
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov