HFNO Flow Rates and Cerebral Oxygenation During Deep Sedation for Cystoscopy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFirat University

About this trial

For Patients and Families

This study aims to investigate how high-flow oxygen therapy affects oxygen levels, especially brain oxygenation, during cystoscopy procedures performed under sedation. The goal is to improve patient safety and comfort by ensuring better oxygen delivery during the procedure. Different oxygen flow rates will be compared, while patients' breathing, oxygen levels, and vital signs are continuously monitored throughout the procedure. All methods used in the study are consistent with routine anesthesia practices, and patient safety remains the highest priority.

For Healthcare Professionals

This prospective randomized controlled study evaluates the effects of different high-flow nasal oxygen (HFNO) flow rates on cerebral oxygenation, peripheral oxygenation, and ventilation parameters in patients undergoing cystoscopy under procedural sedation. The primary aim is to determine the contribution of HFNO to sedation safety and to provide clinical evidence regarding the optimal flow rate. In addition, hypoxemia incidence, airway intervention requirements, hemodynamic variables, and sedation depth are being analyzed.

Eligibility criteria

Qualifiers

Age ≥18 years

Scheduled to undergo elective cystoscopy under procedural sedation in an operating room setting

American Society of Anesthesiologists (ASA) physical status classification I-III

Ability to provide written informed consent

Disqualifiers

Known neurological disorders

History of ischemic or hemorrhagic stroke

Peripheral artery disease

Vasculitis

Trial design

Treatments tested in this trial

  • High-Flow Nasal Oxygen 40 L/min (HF40)
  • High-Flow Nasal Oxygen 55 L/min (HF55)
  • High-Flow Nasal Oxygen 70 L/min (HF70)

Treatment groups

200 Participants
are divided into 3 treatment groups

Sponsors and collaborators