High Definition Profiling of Ovarian Cancer Ascites

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorEuropean Institute of Oncology

About this trial

This project entails the collection of a prospective cohort of ascites (AS) samples from High Grade Serous Ovarian Cancer (HGSOC) patients.

High Grade Serous Ovarian Cancer (HGSOC) is a major cause of cancer-related mortality, due to the late-stage diagnosis and failure of surgery and chemotherapy (CHT) to eradicate the disease with no significant improvement in overall survival.

The primary objective of the project is to generate a comprehensive map of ascites cell components, detailing both their intrinsic features and the landscape of cellular interactions mediated by soluble factors in ascitic fluid.

Eligibility criteria

Qualifiers

Patients with suspicious or confirmed ovarian cancer pathology undergoing debulking surgery

Diagnosis of high grade serous ovarian cancer confirmed by histopathology assessment

Patients who provided written informed consent

Disqualifiers

HIV-positive patients

HBV-positive patients

HCV-positive patients

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

No trial groups listed

Sponsors and collaborators