High Dose Radiotherapy for Palliation (Hi-D)
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBritish Columbia Cancer Agency
The goal of this clinical trial is to evaluate the feasibility of single-blind randomization between two palliative regimens - standard 24 Gray in 3 fractions vs a high-dose (Hi-D) 27 Gray in 3 fractions with dose escalation within the tumor in participants with bulky metastatic cancer.
The main question
Age 18 or older.
Able to provide informed consent
Patient has histologically confirmed solid tumour malignancy
ECOG performance status 0 - 2
- Hematologic malignancy.
Disease limited to intracranial sites
Serious medical co-morbidities precluding radiotherapy
Bone metastases with no soft tissue component