High Dose Radiotherapy for Palliation (Hi-D)

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorBritish Columbia Cancer Agency

About this trial

The goal of this clinical trial is to evaluate the feasibility of single-blind randomization between two palliative regimens - standard 24 Gray in 3 fractions vs a high-dose (Hi-D) 27 Gray in 3 fractions with dose escalation within the tumor in participants with bulky metastatic cancer.

The main question

Eligibility criteria

Qualifiers

Age 18 or older.

Able to provide informed consent

Patient has histologically confirmed solid tumour malignancy

ECOG performance status 0 - 2

Disqualifiers

- Hematologic malignancy.

Disease limited to intracranial sites

Serious medical co-morbidities precluding radiotherapy

Bone metastases with no soft tissue component

Trial design

Treatments tested in this trial

  • Palliative Radiotherapy
  • Palliative Radiotherapy

Treatment groups

20 Participants
are divided into 2 treatment groups

Sponsors and collaborators