About this trial
To clarify the clinical efficacy of high-frequency rTMS on patients with post-stroke cognitive impairment, fNIRS and EEG techniques were used to observe the changes in brain functional activities of patients with post-stroke cognitive impairment after rTMS treatment, and to clarify the neuroregulatory effect of rTMS on patients with post-stroke cognitive impairment.
Eligibility criteria
Qualifiers
Meets the diagnostic criteria for stroke as stipulated in the "Guidelines for the Prevention and Treatment of Stroke in China (2021 Edition)", and the initial stroke diagnosis is confirmed by cranial CT or MRI examination, and is confirmed as the initial onset;
The disease course is 1-12 months;
Has cognitive impairment (MoCA < 26 points, education years ≤ 12 years, add 1 point to the score result);
Age 35-75 years old, gender not limited;
Disqualifiers
Has a history of brain tumors, brain trauma, epilepsy or mental disorders;
Had cognitive impairment before the stroke;
Underwent craniotomy or had a skull defect;
Had implanted metal or electronic devices (such as cardiac pacemakers, cochlear implants, deep brain stimulators, aneurysm clips, internal fixation devices after ventriculoperitoneal shunt surgery, etc.);
Trial design
Treatments tested in this trial
- sham repetitive transcranial magnetic stimulation
- repetitive transcranial magnetic stimulation