The purpose of this study is to determine whether a 16-week virtual, home-based, high-intensity interval training (HIIT) exercise program will improve physical, cognitive, and emotional health among young adult survivors of pediatric brain tumors.
The names of the study interventions involved in this study are/is:
* High-Intensity Interval Training (HIIT)
Written informed consent prior to any study-related procedures.
At time of study are a young adult, aged 18-45 years.
Histologically diagnosed brain tumor during childhood, or currently diagnosed with an IDH-mutant glioma (diagnosed > 18 years).
Are at least 2 years post tumor-directed therapy for pediatric brain tumor survivors, or at least 1 year since their most recent surgery, radiation or chemotherapy treatment for IDH-mutant glioma patients (or are deemed able to participate in the study based on the assessment of their treating physician). IDH-mutant glioma patients can participate while on maintenance therapy with an IDH inhibitor.
Diagnosis of primary spinal cord tumor.
Pre-existing medical conditions such as uncontrolled tumor-related epilepsy, cardiopulmonary disease, or metabolic diseases that could exacerbate with exercise.
Patients with evidence of progressive CNS or systemic cancer in the last 3 months.
People who are pregnant, or plan to become pregnant during study duration will be excluded due to the unknown nature of exercise on developing fetuses.
Dana-Farber Cancer Institute
Lead sponsor
Stahl Family Charitable Foundation
Collaborator
The Childhood Brain Tumor Foundation
Collaborator
Pedals For Pediatrics
Collaborator