High-resolution Magnetic Resonance Vessel Wall Imaging of Plaques

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorShanghai Jiao Tong University Affiliated Sixth People's Hospital

About this trial

The primary objective of this study is to investigate the predictive value of High-resolution magnetic resonance vessel wall imaging for future stroke occurrence in patients with moderate to severe intracranial and extracranial artery stenosis.

The secondary objective is to explore the predictive value of baseline high-resolution magnetic resonance vessel wall imaging for plaque progression.

Eligibility criteria

Qualifiers

At least 18 years old;

Medium or severe stenosis of the internal carotid artery, middle cerebral artery, V4 segment of vertebral artery or basilar artery [stenosis degree: 50% ~ 99%, confirmed by CTA, MRA or DSA];

Accept high resolution magnetic resonance angiography; The patient or the legal representative of the patient is able and willing to sign an informed consent form

Disqualifiers

Non-atherosclerotic intracranial and extracranial artery stenosis, such as dissection, smoke disease, etc.;

There are contraindications to MRI, such as claustrophobia, metal implants, etc.;

Renal insufficiency, elevated serum creatinine (more than twice the upper limit of normal);

Patients with severe cardiopulmonary diseases were considered unsuitable for this study;

Trial design

Treatments tested in this trial

  • Not listed

Trial groups

605 Participants
are grouped into 1 trial group