About this trial
The primary objective of this study is to investigate the predictive value of High-resolution magnetic resonance vessel wall imaging for future stroke occurrence in patients with moderate to severe intracranial and extracranial artery stenosis.
The secondary objective is to explore the predictive value of baseline high-resolution magnetic resonance vessel wall imaging for plaque progression.
Eligibility criteria
Qualifiers
At least 18 years old;
Medium or severe stenosis of the internal carotid artery, middle cerebral artery, V4 segment of vertebral artery or basilar artery [stenosis degree: 50% ~ 99%, confirmed by CTA, MRA or DSA];
Accept high resolution magnetic resonance angiography; The patient or the legal representative of the patient is able and willing to sign an informed consent form
Disqualifiers
Non-atherosclerotic intracranial and extracranial artery stenosis, such as dissection, smoke disease, etc.;
There are contraindications to MRI, such as claustrophobia, metal implants, etc.;
Renal insufficiency, elevated serum creatinine (more than twice the upper limit of normal);
Patients with severe cardiopulmonary diseases were considered unsuitable for this study;
Trial design
Treatments tested in this trial
- Not listed