Histopathological Analysis of Renal Biopsies With Dynamic Full-field Optical Coherence Tomography, a Comparison to Conventional Histopathological Findings for the Diagnosis of Either Acute Kidney Injury or Chronic Kidney Disease in Routine Practices (NEPHROCT)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier William Morey - Chalon sur Saône

About this trial

Kidney biopsy play a key role for the investigation of either acute kidney injury or chronic kidney disease. Despite possible complications due to the invasive nature of the biopsy, such procedure is still essential in a number of clinical situations to improve the diagnosis specificity of kidney disease, better inform about its prognosis and guide the management of a future treatment. Pursuing the idea to improve both performance and rapidity associated with the histopathological analysis of kidney biopsy, with a possible recourse to artificial intelligence-based renal pathology, the present study intends to assess the impact of direct histopathological examination of kidney biopsy with dynamic full-field optical coherence tomography in routine practices for the diagnosis of either acute kidney injury or chronic kidney disease.

Eligibility criteria

Qualifiers

patients > 18 years of age with suspected acute kidney injury requiring biopsy in the nephrology department

patients > 18 years of age with suspected chronic kidney disease requiring biopsy in the nephrology department

Disqualifiers

inability to perform dynamic full-field optical coherence tomography observation at the moment of kidney biopsy

Trial design

Treatments tested in this trial

  • Dynamic full-field optical coherence tomography analysis of kidney biopsy

Treatment groups

50 Participants
are divided into 1 treatment group

Sponsors and collaborators

Centre Hospitalier William Morey - Chalon sur Saône

Lead sponsor

Centre Hospitalier Universitaire Dijon

Collaborator