HIV-1 Non-group M in Cameroon : Study of Genotypic and Phylogenetic Diversity (OBSOCAM)

ConditionHIV Infection
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age21+
SponsorANRS, Emerging Infectious Diseases

About this trial

The aim of the study is to study the genotypic characteristics of HIV-1 non-M circulating in the whole Cameroon and their genetic evolution.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All available samples tested positive for HIV during the national Health survey of Cameroon in 2011 And 2018

All Individuals who came to Centre Pasteur in Yaoundé or Garoua for HIV screening or viral load monitoring.

Disqualifiers

Insufficient quantity or degraded Dried Blood Spot samples

All HIV-positive individuals aged less than 21 years, infected with a Group M HIV-1 virus, or those who refused to participate in the study

Trial population

Retrospective phase : Dried Blood Spot samples tested positive for HIV during the Demographic health surveys in Cameroon 2011 and 2018 surveys, serotyping for HIV. Prospective phase : Individuals who came to Center Pasteur Cameroon in Yaoundé or Garoua for HIV screening or viral load monitoring, serotyping of HIV for positive samples.

Trial design

Design model

Cohort

Time perspective

Other

Treatments tested in this trial

  • Prospective

    Diagnostic test

    Blood samples will be collected in order to meet the objectives of this substudy and possibly for complementary research

Treatment groups

220 Participants
are divided into 2 treatment groups
Group A: Retrospective1 intervention
Group B: Prospective1 intervention

Trial outcomes

Primary outcomes

1

Prevalence of non-M HIV-1 in Cameroon

Number of participants infected with non-M HIV-1 included compared to the total expected number of inclusions

Time frame
1 day

Secondary outcomes

1

Investigate the current molecular epidemiology of resistance in non-M HIV-1 variants in Cameroon

Proportion of non-M HIV-1 samples characterized genotypically among the samples collected from participants included in the project

Time frame
1 Day

Other outcomes

1

Study the current molecular epidemiology of HIV 1 non-M variant resistance in Cameroon

Proportion of non-M HIV-1 samples characterized for resistance among the samples collected from participants included in the project

Time frame
1 day

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

ANRS, Emerging Infectious Diseases

Lead sponsor

University Hospital, Rouen

Collaborator

Centre Pasteur du Cameroun

Collaborator

This trial is not recruiting at the moment. You can still explore other options: