Homburg Renal Evaluation Study on the Clinical Utility of Early AKI Diagnosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversität des Saarlandes

About this trial

Critically ill patients are at risk of developing a sudden decrease of kidney function which may be detected by a decrease in urine output or is diagnosed on the basis of blood tests for substances normally eliminated by the kidney, primarily creatinine.

Because it takes about 24 hours for the creatinine level to rise, even if both kidneys have ceased to function, better markers are needed.

This trial is investigating if the marker urinary dickkopf-3 (uDKK3) allows an early prediction of a sudden decrease of kidney function.

Eligibility criteria

Qualifiers

Patients treated on the intensive care units of Saarland University Hospital.

Disqualifiers

Patients on renal replacement treatment before admission to the intensive care unit.

Patients with chronic kidney disease stage CKD G3b or below.

Known kidney disease.

Kidney transplantation.

Trial design

Treatments tested in this trial

  • DKK-3

Treatment groups

No treatment groups listed

Sponsors and collaborators