Hot Flashes and Neurovascular Function in Women

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age40-60
SponsorMayo Clinic

About this trial

Women who experience hot flashes are at greater risk for hypertension and other cardiovascular disease. Neurovascular control mechanisms are likely to play an important role in this relationship. As such, these studies are designed to provide a major step forward in understanding the link between hot flashes and neurovascular dysfunction and, by extension, cardiovascular disease in women.

Eligibility criteria

Qualifiers

Non-smokers.

Non-obese.

Have at least one ovary.

Free from cardiovascular disease.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Sympathoexcitatory stressors
  • Sodium Nitroprusside
  • Acetylcholine
  • Terbutaline
  • Norepinephrine

Treatment groups

120 Participants
are divided into 1 treatment group

Sponsors and collaborators

Mayo Clinic

Lead sponsor

National Institutes of Health (NIH)

Collaborator

National Heart, Lung, and Blood Institute (NHLBI)

Collaborator