About this trial
The goal of this clinical trial is to learn how different protein types affect the body's metabolism and immune system in healthy adults. The main questions it aims to answer are:
Does drinking smoothies with animal-based or plant-based protein change the level of amino acids like leucine in the blood?
Does adding leucine to a plant-based smoothie make the body respond like it does to an animal-based smoothie?
Participants will:
Come to the research clinic for 3 study visits
Drink a high-protein smoothie at each visit (one with animal protein, one with plant protein, and one with plant protein + leucine)
Give blood samples before and 1 and 3 hours after each smoothie
Researchers will look at how the body's metabolism and immune system respond. They are especially interested in a pathway called mTOR, which helps control how cells use nutrients and may be involved in heart disease like atherosclerosis.
All smoothies are prepared to meet Halal and Kosher dietary guidelines.
Eligibility criteria
Qualifiers
Age 18-65 years
BMI 18.5-29.9 kg/m²
Generally healthy, without known chronic illness and/or treatment with chronic medications
Willing to comply with dietary restrictions and study procedures
Disqualifiers
History of cardiovascular disease, diabetes, or autoimmune disorders
Active use of anti-inflammatory, immunomodulatory, or lipid-lowering medications
Renal or hepatic dysfunction
Pregnancy or breastfeeding
Trial design
Treatments tested in this trial
- Animal-Based Protein Smoothie
- Plant-Based Protein Smoothie
- Plant-Based Protein Smoothie with Leucine