How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age75+
SponsorUniversity of Aarhus

About this trial

The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures. The main question the trial aims to answer is:

Do patients aged 75 and older with hip fractures benefit from earlier treatment of anemia (low blood count) to reduce the risk of delirium?

Researchers will compare early diagnosis and treatment of bleeding with standard care to determine if it helps lower the risk of developing delirium.

Participants will:

Undergo blood tests, have their vital signs monitored, and be screened for delirium three times a day for the first 48 hours after surgery.

Receive blood transfusions promptly if their hemoglobin levels fall below a specified threshold.

Attend a follow-up visit at 30 days to assess cognitive function and overall quality of life.

Attend another follow-up at 90 days to evaluate hospital readmissions and survival.

Eligibility criteria

Qualifiers

Hip fracture

Disqualifiers

Pathological hip fracture

Periprosthtic fracture

Unable to speak or understand Danish

Does not wish to recieve blood transfusion

Trial design

Treatments tested in this trial

  • Blood Transfusion
  • Standard care

Treatment groups

198 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Aarhus

Lead sponsor

Gødstrup Hospital

Collaborator

Aarhus University Hospital

Collaborator