About this trial
THE STUDY AIMS to constitute the largest group of patients with major memory impairment resulting from various etiology and specific lesions of the medial temporal lobe (MTL) and use a combined psychometric and neuroimaging approach to study the factors allowing these patients to successfully learn new semantic information.
Eligibility criteria
Qualifiers
Patients aged between 18 and 70 years
Living in France since less than 20 years, being able to understand the French language, and have basic cultural knowledge as evaluated in classical clinical consultation
Written agreement to participate in the study
Intellectual capacities compatible with the cognitive tasks and signing of consent
Disqualifiers
Subjects under the age of 18 or over 70
Contraindications for MRI (examples: wearers of a pacemaker or cardiac defibrillator, implanted equipment activated by an electrical, magnetic or mechanical system, wearers of haemostatic clips for intracerebral aneurysms or carotid arteries, wearers of orthopedic implants, claustrophobic)
Refusal to be informed of an anomaly detected during the MRI
Trial design
Treatments tested in this trial
- MRI
- Psychometric
Treatment groups
Sponsors and collaborators
University Hospital, Toulouse
Lead sponsor
National Research Agency, France
Collaborator