Hyaluronic Acid for Prevention of Post-Intubation Sore Throat and Hoarseness

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19-80
SponsorPusan National University Yangsan Hospital

About this trial

The goal of this clinical trial is to find out whether applying Endotra Gel, a hyaluronic acid-based gel, to the endotracheal tube can help reduce sore throat and hoarseness after surgery.

These symptoms are common after general anesthesia when a endotracheal tube is placed into the trachea. They can cause discomfort and affect patient recovery.

The main questions this study aims to answer are:

* Does Endotra Gel reduce the chance of having a sore throat after surgery? * Does it help improve hoarseness or coughing after surgery?

Participants in this study will:

* Undergo general anesthesia for breast cancer surgery * Be randomly assigned to one of two groups:

* One group will receive Endotra Gel applied to the endotracheal tube before intubation * The other group will have standard care with no gel * Be monitored for sore throat, hoarseness, and coughing right after surgery and on the day after surgery * Answer questions about their symptoms and satisfaction with their recovery The results will help researchers learn whether using Endotra Gel during intubation can improve patient comfort and reduce airway irritation after surgery.

Eligibility criteria

Qualifiers

Adults aged 19 to 80 years

Scheduled to undergo breast cancer surgery under general anesthesia with endotracheal intubation

American Society of Anesthesiologists (ASA) physical status I to III

Disqualifiers

Mallampati classification of III or higher

Recent upper respiratory infection or symptoms of upper airway infection

Pre-existing laryngeal disease or chronic respiratory conditions (e.g., asthma, chronic bronchitis)

Current use of systemic steroids

Trial design

Treatments tested in this trial

  • Endotra Gel

Treatment groups

92 Participants
are divided into 2 treatment groups

Locations

This trial has no locations